The UMC Utrecht has developed an in-vitro measurement method to measure concentrations in infusion lines of multi-infusion while simulating several manual disturbances in one or more pumps. This method relies on spectrophotometry and flow meters. The spectrophotometry is used to determine the concentration of added dies whereas the flow meters measure the flow rate of [...]
Medication protocols allow clinicians to administer the correct amount of medication to the patient. Medication protocols may include any procedure necessary to accomplish this goal safely, i.e. to prevent medical/medication errors. In cooperation with the JRP partners, the UMC Utrecht has compiled and disseminated a survey about medication protocols amongst European hospitals. The aim was [...]
DTI and METAS have developed a flow meter performance tester for pulsating flow. The METAS setup covers a flow rate range of 1 ml/min to 1 ml/min with uncertainties ranging from 0.2% to 2.7%, depending on the flow rate and the fit window used. The DTI setup covers a flow rate range of 1 ml/min [...]
At the 2nd International Conference on Microfluidic Handling systems (MFHS 2014), MeDD presented various results. Click here for the proceedings of the volumetric-based primary standard of VSL. Click here for the proceedings of the gravimetric standard of METAS.
M Ahrens, St Klein, B Nestler and C Damiani This work focuses on the design and characterization of a system for measuring and calibration of liquid micro-flows down to 5 nL min−1. The experimental setup relies on a telecentric imaging system mounted on a high-precision, computer controlled linear stage to track a moving liquid meniscus in a [...]
In this work we develop a physical model which describes the behavior of an unsteady flow measured with a gravimetric set up. The model is based on equation for the physical shape of the interfaces between different fluids in the beaker (air-oil and oil-water) and on models of contact angles between these interfaces and the [...]
The aim of this work is to develop a physical model for the thermal processes that occur in the nano-flow generator of VSL, which is based on thermal expansion of water enclosed in a titanium reservoir. The model aims at establishing a numerical model for the flow rate in order to estimate the uncertainties involved. [...]
Within MeDD various primary standards are developed for the calibration of infusion devices and flow meters. These standards, or calibration facilities, have been developed for liquid flow rates at ambient pressure and temperature. The flow rate range per standard varies somewhat; the combined flow rate range is between 1 nl/min up to 10 ml/min. Goal [...]
Defining the regions (1 – 1000) μl/min as microflow and (1 – 1000) nl/min as nanoflow, this white paper describes various principles for a primary realization of the measurement. In this document we briefly describe some common principles for flow rate calibrations. Typically, the gravimetric approach is used for microflow rates. For nanoflow rates potential [...]
The second European Flow Measurement Workshop for ultrasonic flowmeters and Coriolis was held in Sintra from 25-27 March 2014. This event organized by the Dutch Metrology Institute (VSL) and the Colorado Engineering Experiment Station Inc. (CEESI), was attended by about 160 participants. The goal of this event focused on the dissemination of new technologies and [...]